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1.
Cureus ; 16(3): e56604, 2024 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-38646380

RESUMO

Introduction As the incidence of periodontal diseases continues to surge, there is a concurrent elevation in the demand for periodontal treatment. Periodontal surgical therapy is done to control and eliminate disease activity. Conventionally, silk sutures have been considered the gold standard for post-operative flap closure that leads to biofilm accumulation and tissue trauma. Cyanoacrylates are alternate options to avoid the limitations. Objective The objective of the study was to assess clinical outcomes by comparing the healing after periodontal flap surgery when secured with 3-0 braided silk suture versus cyanoacrylate. Methodology Twenty surgical sites from 10 patients with moderate to severe periodontitis were selected and randomly divided into two groups after phase-1 therapy: the test group (isoamyl 2-cyanoacrylate) and the control group (3-0 silk braided suture). Post-operative wound healing, pain assessment using a verbal rating scale (VRS), and analgesic tablets taken were evaluated on the third, fifth, seventh, and 14th days. Statistical analysis was done using the ANOVA test with the post-hoc Bonferroni test. Results There was no statistically significant difference between the VRS and wound healing index at different levels of intervals during intergroup comparison, but the number of analgesics consumed post-operatively was less in the test group as compared to the control group. Conclusion The present study concluded that isoamyl 2-cyanoacrylate can be used as an alternative to conventional silk sutures as it decreases post-operative pain and discomfort.

2.
Indian J Dent Res ; 29(6): 808-811, 2018.
Artigo em Inglês | MEDLINE | ID: mdl-30589012

RESUMO

Taurine or 2-aminoethanesulfonic has many fundamental biological roles such as conjugation of bile acids, antioxidation, osmoregulation, membrane stabilization, and modulation of calcium signaling. It is essential for cardiovascular function and development and function of the skeletal muscle, the retina, and the central nervous system. Functions of taurine include osmoregulation; membrane stabilization; modulation of calcium levels; and antioxidation, antiapoptotic, anti-inflammatory, and antilipid activities. Taurine was first discovered as a component of ox (Bos taurus, from which its name is derived) bile in 1827; it had taken over a century before insights into its physiological functions were made. The present review throws light on the multifactorial properties of taurine and its potential to be used in periodontal therapy.


Assuntos
Doenças Periodontais/tratamento farmacológico , Taurina/uso terapêutico , Animais , Anti-Inflamatórios , Antioxidantes , Apoptose/efeitos dos fármacos , Cálcio/metabolismo , Células Cultivadas , Humanos , Fármacos Neuroprotetores , Osteogênese/efeitos dos fármacos , Taurina/química , Taurina/metabolismo , Taurina/farmacologia
3.
Indian Heart J ; 68(4): 572-5, 2016.
Artigo em Inglês | MEDLINE | ID: mdl-27543484

RESUMO

Cardiovascular disease trends, complications, and associated therapeutics impact the dental health and treatment. Such patients require special consideration with regard to when and which dental treatment is appropriate and what precautions are required. Alertness to potential oral adverse drug reactions enables referral of patient's to his physician or cardiologist. Cardiovascular drugs are also known to have mild to potentially fatal drug interactions. Dental professionals may be the first line of defense in the detection and referral of a patient suspected of having cardiovascular disease, an uncontrolled disease status, or oral adverse drug reactions, and they have a key role to play in oral and systemic disease prevention and treatment, in partnership with the patient and his physician.


Assuntos
Doenças Cardiovasculares/prevenção & controle , Gerenciamento Clínico , Promoção da Saúde , Saúde Bucal , Higiene Bucal/normas , Periodontite/complicações , Doenças Cardiovasculares/epidemiologia , Doenças Cardiovasculares/etiologia , Saúde Global , Humanos , Cooperação do Paciente , Periodontite/terapia , Prevalência , Fatores de Risco
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